The postdoctoral associate is expected to use biochemical, molecular biology, cell culture and animal models. Will also develop and evaluate biologics that concurrently engage adipocyte metabolism and gap junction activity to improve the efficacy of the starting molecule.
The postdoctoral associate is expected to use biochemical, molecular biology, cell culture and animal models to:
- Characterize the gap-junction dependent function of Connexin43 in enhancing pharmaceutical agents targeting adipose tissue metabolism.
- Characterize how adipose-tissue Connexin43 gap junction affects breast milk production and the hormonal profile of the breast milk.
- Study a gap-junction independent function of Connexin43 in adipocytes, including characterizing an adipose tissue-specific mitochondrial-targeted Connexin43 animal on normal chow and high-fat diet.
- Develop screening assays, engage in the screening for receptors of a pharmaceutical Connexin43 gap junction activating peptide, and understand the signaling cascade downstream of this yet to be found receptor.
The postdoc will also develop and evaluate biologics that concurrently engage adipocyte metabolism and gap junction activity to improve the efficacy of the starting molecule.Minimum Qualifications
- Education Required: Ph.D in Basic Science, Health Science, or a related field.
- Experience Required: None Required.
- Should be motivated to pursue a career in science, team-oriented, proactive, dedicated, honest, critical, and open-minded.
- If the candidate graduated/will graduate outside of the U.S., he/she is required to demonstrate English proficiency level.
- Two first-author publications are expected.
- Prior experience in the areas of molecular biology and protein engineering.
- Experience in metabolism is a plus.
Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.
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