Transforming Medicine Through the Practice and Science of Genetics and Genomics
The Department of Molecular and Human Genetics at Baylor College of Medicine is transforming medicine by expanding the role of genetics and genomics in science and medicine through major discoveries and integration of basic research, clinical, and diagnostic activities. Our talented faculty, trainees and staff have designed an environment that promotes and supports diversity, inclusion, and equity.
Our department consistently ranks first in the nation in funding from the National Institutes of Health. In addition to numerous NIH, National Science Foundation, March of Dimes, and other competitive research grants, the faculty have received national recognition and support from the Pew Foundation and the Howard Hughes Medical Institute. Our educational programs attract the most highly qualified candidates. Our clinical genetics program, the largest in the country, offers patients unparalleled, single-source genetic testing and services.
The overarching theme of Dr. Zhang's laboratory is to understand the genomic and epigenomic regulation of the cardiovascular system in health and in disease with an emphasis on heart failure and cardiomyopathies. This research program studies the circadian gene regulation in heart failure. The scope includes transcriptional regulation through core clock factors as well as post-transcriptional regulation such as alternative splicing. We use diverse experimental approaches including genomics/epigenomics, molecular biology, cell biology and mouse models.Job Duties
- Carry out independent research project, including planning the experiment, performing the experiment, collecting and analyzing the results.
- Communicate research professionally, including presenting and discussing research both verbally and in writing.
- Collaborate with other lab members.
- Manage mouse colonies.
- Collect samples from mice.
- Cell culture, including cell lines and primary cells.
- Perform qPCR, immunofluorescence, in situ, microscopy, ChIP, co-IP, cloning, etc.
- MD or Ph.D in Basic Science, Health Science, or a related field.
- No experience required.
- PhD in Molecular Biology, Genetics, Cell Biology, or related fields.
- A strong interest in the genomics/epigenomics of cardiovascular disease.
- Expertise in molecular biology.
- Basic handling of mice.
- Additional experience in bioinformatics.
- The ideal candidate will be a highly self-motivated recent graduate and have a track record of publications (first-authored publications in respected journals). Senior post-doc with relevant experience will also be considered.
Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.
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