Research Assistant II – Lung Stem Cell Biology
LAB INFO/POSITION OVERVIEW:
The Richmond Lab is broadly interested in the role of the airway epithelium in chronic obstructive pulmonary disease (COPD). Recent work from other labs has shown that stem cell variants that are normally present in small numbers in health are expanded in COPD. This project will evaluate environmental factors associated with abnormal stem cell expansion and seek to understand how these clones alter the local tissue microenvironment using a mouse model. Prior experience in cell culture, preferably primary cell culture, is preferred. Experience in bulk or single-cell RNA-sequencing would be helpful but is not required. Applicants must be willing to work with mice, but prior experience with animal husbandry is not required.
Under moderate supervision, set up, conduct experiments, and continue research projects following protocols including the appropriate recording of data and reporting of standard or variant results. Assist in other laboratory and research functions.
- Under moderate supervision, conduct and evaluate experiments and assays
- Understand and follow experimental protocols (may include animal handling, tissue culture, etc.)
- Record, compile, interpret, and communicate data/results
- Follow University safety protocols (may include use of combustibles, radioactivity, toxic material, and/or carcinogens)
- Perform calculations involving molarity, % solutions, and serial dilutions
- Prepare, operate and troubleshoot equipment in experimental procedures
- Read and follow all equipment manuals
- Maintain and repair equipment according to manufacturer and University guidelines
- Ensure Laboratory is prepared for experiments
- Maintain inventories
- Maintain sterile conditions as required
- Prepare reagents
- Demonstrate an understanding of acceptable procedures and techniques
- Recognize problems and suggest solutions
- Assist in modifications as directed
- Provide appropriate written documentation of experiments
- Prepare preliminary research progress reports
- Summarize test results appropriately
The Division of Allergy, Pulmonary and Critical Care is directed by Dr. Timothy Blackwell and its mission is to:
- deliver world-class clinical care to patients with allergic diseases, pulmonary conditions, and critical illness through employing a collaborative, multi-disciplinary approach with a wide range of clinical programs.
- lead in the development of cutting-edge, patient-focused research that extends from basic discoveries to clinical implementation.
- provide state-of-the-art education and training including a strong fellowship program to inspire and nurture the next generation of leaders in allergy and immunology, pulmonary medicine, and critical care.
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VUMC Recent Accomplishments
Because we are committed to providing the best in patient care, education and research, we are proud of our recent accomplishments:
· US News & World Report: #1 Adult Hospital in Tennessee and metropolitan Nashville, named to the Best Hospitals Honor Roll of the top 20 adult hospitals, 10 nationally ranked adult specialty programs, with 3 specialties rated in the top 10 nationally, Monroe Carell Jr. Children's Hospital at Vanderbilt named as one of the Best Children's Hospital in the nation, with 10 out of 10 pediatric specialties nationally ranked.
· Healthcare's Most Wired: Among the nation's 100 “most-wired” hospitals and health systems for its efforts in innovative medical technology.
· Becker's Hospital Review: named as one of the “100 Great Hospitals in America”, in the roster of 100 Hospitals and Health Systems with Great Oncology Programs and to its list of the 100 Hospitals with Great Heart Programs.
· The Leapfrog Group: One of only 10 children's hospitals in the to be named at Leapfrog Top Hospital.
· American Association for the Advancement of Science: The School of Medicine has 112 elected fellows
· Magnet Recognition Program: Received our third consecutive Magnet designations.
· National Academy of Medicine: 22 members, elected by their peers in recognition of outstanding achievement
· Human Rights Campaign Healthcare Equality Index: 6th year in a row that Vanderbilt University Medical Center was a Leader in LGBTQ Healthcare Equality.
Bachelor's Degree (or equivalent experience) and 2 years experience
- Occasional: Sitting: Remaining in seated position
- Occasional: Standing: Remaining on one's feet without moving.
- Occasional: Walking: Moving about on foot.
- Occasional: Lifting under 35 lbs: Raising and lowering objects under 35 lbs from one level to another
- Occasional: Push/Pull: Exerting force to move objects away from or toward.
- Occasional: Bending/Stooping: Trunk bending downward and forward by bending spine at waist requiring full use of lower extremities and back muscles
- Occasional: Reaching below shoulders: Extending arms in any direction below shoulders.
- Occasional: Handling: Seizing, holding, grasping, turning or otherwise working with hand or hands.
- Occasional: Vision: Clarity of near vision at 20 inches or less and far vision at 20 feet or more with depth perception, peripheral vision, color vision.
- Occasional: Noise: May include exposure to occupational noise levels which equal or exceed an 8-hr time-weighted average of 85 decibels, requiring enrollment in VUMC's Hearing Conservation Program which includes training, use of hearing protection, and periodic audiometry.
- Continuous: Communication: Expressing or exchanging written/verbal/electronic information.
- Occasional: Chemicals and Gasses: Medications, cleaning chemicals, oxygen, other medical gases used in work area.
- Occasional: Pathogens: Risk of exposure to bloodborne pathogens and other contagious illnesses.
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